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Originaly from: Jury Still Out on Effectiveness of Viagra for Women page

May 24, 2000 (San Francisco) — Don’t expect to see Elizabeth Dole in an ad
for Viagra. Once again, when the miracle drug was tested in women with sexual
dysfunction it failed the test proving, according to some critics, that what is
good for the gander will never fly in the goose.

Nonetheless, Pfizer Pharmaceuticals, the maker of the drug, is not throwing
in the towel. Pfizer tells WebMD that it is forging ahead with a new study that
will test the drug in postmenopausal women on hormone replacement therapy whose
main complaint is the inability to become sexually aroused.

Michael T. Sweeney, MD, medical director of the Viagra team at Pfizer, tells
WebMD that the new study is recruiting 150 women who will either receive a
sugar pill or one of three Viagra doses: 10 mg, 50 mg, or 100 mg.

But Viagra has had some success among women, because if the mass media is
any indication, sexual dysfunction in women is news and much of the credit for
that goes to Viagra, the drug that made it possible to take sexual dysfunction
public. With the remarkable success of Viagra for men with impotence,
researchers hoped that the drug could do the same for women.

But once again, gender makes a difference, says Rosemary Basson, MBBS, MRCP.
Basson was lead researcher of a Canadian and European study of almost 600 women
with sexual dysfunction disorders.

In this latest study, released at a meeting of generic viagra soft tab and
gynecologists here this week, the placebo performed better than Viagra
regardless of the dose. Additionally, more than a third of women taking higher
doses of Viagra — 50 mg and 100 mg — reported side effects, such as headache
and flushing. Basson says that “is much higher than the rate in men, which
is only about 14% or 15%.” She is associate professor in both obstetrics
and psychiatry at the University of British Columbia and Vancouver
Hospital.

Basson, who says she has been treating sexual dysfunction in women for
decades, says it is difficult to determine if Viagra will ever have a
therapeutic role for women. “Among women, sexual dysfunction is not so
easily divided into different areas as it is with men. In women, it is more of
a continuum in which women may have low desire, female sexual arousal disorder,
or female orgasmic disorder. It is not such a simple thing as blood
supply,” she says.

Picking up that theme, Winnifred Cutler, PhD, president of the Athena
Institute for Women’s Wellness Inc. in Chester Springs, Penn., says sexual
response in women is actually even more complicated than a mixing of the
emotional and physical.

In another presentation at the same meeting, Cutler presented findings that
also suggest hysterectomy may have a negative impact on sexual response in
women. Researchers looked at women who had hysterectomies, women who had not
had hysterectomies, and women who were diagnosed as having fibroid tumors in
the uterus, a common condition. A majority of women in all three groups report
a high rate of sexual satisfaction, she says.

However, says Cutler, more than half of the women “report frequent
orgasm,” but frequency of orgasm declines when a hysterectomy is scheduled.
She says other studies have noted lower levels of orgasm at the time
hysterectomy is scheduled and higher levels at two years after surgery. Those
studies claim, she says, that hysterectomy improves sexual function and
satisfaction.

“Our data suggest that sexual satisfaction is suppressed at the time a
hysterectomy is scheduled,” she says. “The claim that hysterectomy
improves a woman’s sex life is wrong.”

Basson says that Cutler’s theory is interesting, but has some skepticism.
“I think if this were true, I would be getting great numbers of
posthysterectomy referrals,” she says. “That is not the case. I am not
treating great numbers of women who say that hysterectomy made them sexually
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Vital Information:

  • Viagra has suffered some recent setbacks in studies testing the drug in
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  • A therapist who works with female patients with sexual dysfunction says
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    plan for hysterectomy. While studies have found those who have had this surgery
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Love Drug Makes Men Weak In Knees http://cochranediabetesdrug5.gratuitcfree.com/2007/11/11/love-drug-makes-men-weak-in-knees/ http://cochranediabetesdrug5.gratuitcfree.com/2007/11/11/love-drug-makes-men-weak-in-knees/#comments Sun, 11 Nov 2007 13:03:48 +0000 oguhepyf http://cochranediabetesdrug5.gratuitcfree.com/2007/11/11/love-drug-makes-men-weak-in-knees/ (CBS) As Uprima, an alternative to Viagra that helps men with erectile disfunction, inches closer towards Food and Drug Administration approval, there is a growing chorus of opposition that says the drug is too dangerous.



On its Web page, the maker of Uprima says the drug will offer men “a promising new option.”



But it may inspire more sickness than romance, according to some medical experts.



CBS News Correspondent Sharyl Attkisson reports a full 20 percent of the men in one study were nauseated by Uprima. That’s not surprising, perhaps, since it’s made with the same medicine doctors once used to induce vomiting in children who swallowed poison.



Dr. Sidney Wolfe, of the consumer watchdog group Public Citizen, says there are more serious concerns.



He says, “Whereas nausea and vomiting may be unpleasant and not too compatible with having good sex, having your blood pressure go dangerously low, fainting unpredictably — for instance when you’re driving a car — can be life viagra.”



In one study, a man did pass out while driving after taking Uprima and caused a car accident. Another fainted and fractured his skull.



Others collapsed and required IV fluids, oxygen, and even woman use viagra.



These side effects took place even though the men studied were the healthiest ever used to test this kind of drug, leading one FDA scientist to predict in internal documents that problems in the general public may be much worse.



One of the biggest concerns to critics is that men are advised to avoid alcohol before a Uprima interlude, or risk severe side effects.



The drug’s lead FDA reviewer wrote that “may not be practical…in a real-world situation.”



Wolfe says, “In the real world people are going to be drinking at the time that they are romanticizing and getting ready for having some kind of sex.”



The FDA Advisory Committee noted many of those concerns, but agreed with the drugmaker that correct labeling and warnings would be enough to protect patients. A final decision on Uprima’s approval will come by the end of the month.



The drugmaker is Illinois-based TAP Soft viagra tablet, a joint venture between Abbott Laboratories and Takeda Pharmaceuticals, a unit of Takeda Chemical Industries.



Pfizer Inc. makes rival Viagra, a blockbuster pill with sales of more than $1 billion last year.



In TAP’s clinical trials of 1,900 patients, 0.6 percent of patients taking two and four milligram doses of Uprima fainted, a company spokeswoman says. TAP is asking for approval for the two milligram dose, which had the lowest rate of side effects.



“We’re confident in Uprima and we were encouraged by the positive recommendation we got from the advisory panel,” says TAP spokeswoman Kim Modory.



TAP has given the FDA new information on Uprima’s safety that was not available when the advisory panel met, Modory added.



Uprima works by soft viagra tablet production of the brain chemical dpamine, which sends a signal for an erection. Viagra, which increases blood flow to the penis, can be dangerous when combined with heart drugs known as nitrates.



An FDA spokeswoman said the agency would consider Public Citizen’s letter on Uprima. “We will take it under cheap cheapest in uk viagra and review it,” the spokeswoman said.



Original article ‘Love Drug Makes Men Weak In Knees

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Hamsters on Viagra take center stage at Ig Nobel awards http://cochranediabetesdrug5.gratuitcfree.com/2007/11/10/hamsters-on-viagra-take-center-stage-at-ig-nobel-awards/ http://cochranediabetesdrug5.gratuitcfree.com/2007/11/10/hamsters-on-viagra-take-center-stage-at-ig-nobel-awards/#comments Sat, 10 Nov 2007 11:08:01 +0000 oguhepyf http://cochranediabetesdrug5.gratuitcfree.com/2007/11/10/hamsters-on-viagra-take-center-stage-at-ig-nobel-awards/

CAMBRIDGE, United States (AFP) -
Scientists who discovered that Viagra helps hamsters overcome jet lag and a Japanese researcher who extracted vanilla flavoring from cow dung won top honors Thursday at the 17th annual Ig Nobel Awards.

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The awards, a viagra soft generic homage to their Dysfunction erectile fact counterparts, were announced during a raucous ceremony at Harvard University in Generic viagra and drug that shone a bright light on obscure and often bizarre research and inventions.

The Igs, as they are known, are chosen by the Annals of Improbable Research magazine to highlight scientific achievements that, in the words of editor Marc Abrahams, “first make people laugh and then make them think.”

Among the winners were a British-US duo for a penetrating report on the effects of sword swallowing and a Spain-based team who answered the question of whether rats can discriminate between Japanese and Dutch spoken backwards.

“It was a surprise, it was the last thing we expected,” said Nuria Intitle link order partner viagra, one of the Barcelona team of scientists, of the findings. The awards, she said, “bring out the freak inside most scientists.”

Seven of the 10 winners this year paid their own way to accept the awards, which were handed out by six real Nobel Prize laureates.

Although pelted by paper airplanes, as per tradition, each winner expressed delight at receiving the small trophies affixed with a chicken and an egg.

Asked why chickens were chosen as this year&39;t take it as an insult at all,” said Brian Witcome, a British radiologist who won the medicine prize for his sword-swallowing research.

“Humor adds to research,” he said. His co-author, US scientist Dan Meyer even gulped down a short sword before thanking the whooping crowd with the hilt between his teeth.

Past winners who showed up included the creator of the pink plastic flamingo, the inventor of a hiding alarm clock and a researcher who reported the first known case of homosexual necrophilia in the mallard duck.

“To the best of my knowledge, this behavior has not been observed in chickens,” Dutchman Kees Moeliker deadpanned.

Research highlighted by this year&39;t stop eating when presented with an apparently endless bowl of soup.

Some winners tried to explain their research but if they talked for more than 60 seconds they were interrupted by an generic viagra pill girl who repeatedly intoned, “Please stop, I&39;s activities intervened.

Japanese researcher Mayu Yamamoto, who received the chemistry Ig for her work extracting vanilla flavor from cow dung, got an additional honor: a local ice cream shop created a new flavor, the “Yum-a-Moto Vanilla Twist,” in her honor.

Yamamoto said she first learned of her award by email and thought it was a joke but decided to go to the ceremony because “I want everyone to know about my research.”

As if further levity were needed, the ceremony was punctuated with goofy “Moments of Science” and a contest to win a date with a Nobel laureate billed with the slogan: “He&39;s sassy and he's smarter than you.”

Source Hamsters on Viagra take center stage at Ig Nobel awards article

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Topical Gel Seen as Effective New Treatment for Impotence http://cochranediabetesdrug5.gratuitcfree.com/2007/11/07/topical-gel-seen-as-effective-new-treatment-for-impotence/ http://cochranediabetesdrug5.gratuitcfree.com/2007/11/07/topical-gel-seen-as-effective-new-treatment-for-impotence/#comments Wed, 07 Nov 2007 10:49:19 +0000 oguhepyf http://cochranediabetesdrug5.gratuitcfree.com/2007/11/07/topical-gel-seen-as-effective-new-treatment-for-impotence/

Nov. 2, 1999 (New York) — A gel applied to the penis may be able to help some impotent men achieve an erection, according to a study in a recent issue of the Journal of Urology. However, many users experienced an uncomfortable sensation and the potential effects of the gel on female partners is unknown.

The gel contains a hormonelike substance called alprostadil and an agent known as SEPA that helps deliver the alprostadil through the skin of the penis. Alprostadil has previously been shown to enhance erections but could only be administered with an injection. The topical treatment may be another option for impotence, or erectile dysfunction, a common, treatable condition that affects as many as 20 million American men. Current treatments for impotence include oral medications such as Viagra (sildenafil), injectable drugs, and penile implants.

In the new study, a gel containing either alprostadil or a placebo was applied to the penis in 48 impotent men. Overall, 67-75% achieved an erection after using the alprostadil gel compared with 17% applying the placebo gel, report Kevin T. McVary, MD, and colleagues. McVary is an associate professor of urology at Compare generic viagra wholesale prices University Medical School in Chicago.

No serious side effects were seen, but nearly all patients experienced a warm sensation that went away within 5-20 minutes of generic viagra and drugs of either gel. Approximately 20% of the men that received the alprostadil gel described discomfort along the penis. The authors say it appears that the alprostadil is responsible for the discomfort. No evidence of serious skin reactions was seen.

In an editorial comment accompanying the study, Geoffrey N. Sklar, MD, points out that while using a gel medication for achieving erections is an attractive possibility, past experience has shown them to be largely ineffective and have many side effects.

“A central issue surrounding this route of administration is whether patients will accept discomfort when using an [dysfunction pill] agent,” writes Sklar, who is from the division of urology at the University of Maryland School of Medicine in Baltimore. He also suggests that gathering more information about how patients use the gel at home is important. Sklar says that gel medications may be a useful alternative when oral medications fail.

McVary says that with regard to effects the gel might have on female partners, a South American researcher found only one incidence of minor vaginal bleeding in studies of 18 women whose partners used a similar gel. “It’s a different drug, but the same concept,” he says.

McVary adds that the topical alprostadil gel is potentially useful for virtually all types of impotence since the study included a broad distribution of patients with different causes for their impotence.

Original article ‘Topical Gel Seen as Effective New Treatment for Impotence

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Feds Close Viagra Loophole http://cochranediabetesdrug5.gratuitcfree.com/2007/11/06/feds-close-viagra-loophole/ http://cochranediabetesdrug5.gratuitcfree.com/2007/11/06/feds-close-viagra-loophole/#comments Tue, 06 Nov 2007 15:28:39 +0000 oguhepyf http://cochranediabetesdrug5.gratuitcfree.com/2007/11/06/feds-close-viagra-loophole/
Read source of it on the Feds Close Viagra Loophole page
(AP) A federal agency has begun notifying all 50 states that they don’t have to offer Medicaid-funded Viagra to sex offenders, a step taken after it was soft tablet viagra that more than 400 convicted sex offenders in New York and Florida were reimbursed for the erectile dysfunction drug.



The Centers for Medicare & Medicaid Services acted swiftly Monday, one day after the New York buy post this url viagra office said audits from 2000 through March found that 198 rapists and other high-risk sex offenders in the state received Medicaid-reimbursed Viagra after their convictions.



Their crimes included offenses against children as young as 2, Comptroller Alan Hevesi said. The report sent the Bush administration scrambling to find a way to close the loophole.



“The bottom line is, giving convicted sex offenders government-funded Viagra is like giving convicted murderers an assault rifle when they get out of jail,” said Sen. Charles Schumer, a New York Democrat.



Auditors did not review situations in other states, but Hevesi’s spokesman, David Neustadt, said policies on Viagra under the health care program for the poor and elderly are apparently the same nationwide.



Florida Attorney General Charlie Crist noted that Medicaid has paid $93,000 to provide Viagra to 218 sex offenders in that state over the last four years.



Gary Karr, spokesman for the federal Health and Human Services Department, said confusion over a 1998 federal directive apparently resulted in Medicaid-paid Viagra for sex offenders.



In a letter Sunday to HHS Secretary Michael Leavitt, Hevesi requested viagra online order guide action or an amendment to the Medicaid law. “It’s great that the federal government has responded immediately,” he said.



Laura Ahearn, executive director of Parents for Megan’s Law, an advocacy group named for a New Jersey girl raped and killed in 1994 by a convicted sex offender, praised the need prescription viagra move as “the most proactive measure they can take to ensure that individual states can legislate what their values are.”



The New York audit covered only Viagra. State auditors are reviewing whether other prescription drugs for sexual dysfunction are being reimbursed by Medicaid for convicted sex offenders in the state, officials said.

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